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Image Search Results
Journal: Cellular and Molecular Life Sciences: CMLS
Article Title: Prenatal treatment with preimplantation factor improves early postnatal neurogenesis and cognitive impairments in a mouse model of Down syndrome
doi: 10.1007/s00018-024-05245-9
Figure Lengend Snippet: Treatment with sPIF restores DYRK1A and BDNF protein levels in the brain of Dp(16)1Yey pups on P6. Evaluation of the DYRK1A protein level in WT pups (vehicle: n = 5; sPIF: n = 5) and Dp(16)1Yey pups (vehicle: n = 3; sPIF: n = 5) ( A ). The brain BDNF protein concentration in WT pups (vehicle: n = 6; sPIF: n = 4) and Dp(16)1Yey pups (vehicle: n = 4; sPIF: n = 6) ( B ). Data are expressed as the mean ± SD and were analyzed in a two-way ANOVA followed by Fisher’s least squares difference test. ** p < 0.01
Article Snippet: The levels of brain-derived neurotrophic factor (BDNF) in brain lysates were measured with a
Techniques: Protein Concentration